CD30 (TNFRSF8) Rabbit Monoclonal Antibody [Clone ID: Ki-3]

CAT#: TA385979

Recombinant Anti-CD30 (Clone Ki-3)


USD 523.00

2 Weeks*

Size
    • 200 ug

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Specifications

Product Data
Clone Name Ki-3
Applications ELISA, FC, IF, IHC
Reactivities Human
Modifications This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
Host Rabbit
Isotype IgG, kappa
Clonality Monoclonal
Immunogen Human CD30.
Specificity The antibody binds to CD30.

The antibody binds specifically to CD30, a cell membrane protein which belongs to the tumour necrosis factor receptor family. Incubation of CD30 positive L540 cells with Ki-3 antibody weakly enhances release of soluble CD30 (in contrast to Ki-4, Ab00475). CD30 is expressed on activated lymphocytes, and binding by its ligands TRAF2 and TRAF5 results in the activation of NF-kappaB, thereby regulating gene expression. CD30 is also associated with Hodgkin Lymphoma, and its expression acts as a tumour marker. Targeting the CD30 antigen with specific monoclonal antibodies is a possible therapy for Hodgkin's lymphoma.
Formulation PBS with 0.02% Proclin 300.
Concentration lot specific
Conjugation Unconjugated
Storage Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Stability 3 years from dispatch.
Gene Name tumor necrosis factor receptor superfamily member 8
Synonyms CD30; D1S166E; KI-1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.