CD252 (TNFSF4) Rabbit Monoclonal Antibody [Clone ID: R4930 (Oxelumab)]

CAT#: TA386011

Recombinant Anti-OX40L (Clone R4930 (Oxelumab))

Product Images

Flow-cytometry using the anti-OX40L antibody [R4930] (Oxelumab) (Ab00536) Human peripheral blood leukocytes were fixed using 2% PFA, permeabilised using 0.5% Triton and stained with unimmunized rabbit IgG antibody (MOPC-21; isotype control, black line) or the rabbit IgG-chimeric version of [R4930] (TA386011, blue line) at a dilution of 1:100 for 1h at RT. After washing, bound antibody was detected using a goat anti-rabbit IgG AlexaFluor® 488 antibody at a dilution of 1:1000 and cells analyzed using a FACSCanto flow-cytometer.

Specifications

Product Data

• Clone Name: R4930 (Oxelumab)
• Applications: FC
• Reactivities: Human
• Modifications: This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
• Host: Rabbit
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Immunogen: Oxelumab binds to human OX40L, the ligand of OX40, stimulatory receptor that is expressed on activated T cells, natural killer (NK) cells and natural killer T (NKT) cells.
• Specificity: Binds to human OX40L.
  
  This antibody binds to the co-stimulatory OX40L, inhibiting its interaction with OX40.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: tumor necrosis factor superfamily member 4
• Database Link:
  Entrez Gene 7292 Human
  UniProt ID P23510
• Synonyms: CD134L; CD252; GP34; OX-40L; OX4OL; OX40L; TXGP1