Cd27 Monoclonal Antibody [Clone ID: LG.3A10]

CAT#: TA386053

Recombinant Anti-CD27 (Clone LG.3A10)

Specifications

Product Data

• Clone Name: LG.3A10
• Applications: FC, IF, IP
• Reactivities: Human, Mouse, Rat
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Immunogen: This antibody was produced by injecting Armenian hamsters intraperitoneally with a mixture of two murine CD27 tag-expressing Armenian hamster fibroblast clones (AR0524 and AR0530) in Freund's adjuvant
• Specificity: This antibody is specific for mouse CD27, which, as in the human system, is largely restricted to cells of the T cell lineage, and is expressed on the great majority of both αβ and γδ T lymphocytes, and thymocytes.
  
  This antibody is specific for murine CD27, and has been used to assess the distribution of CD27 expression using IF, FC and IP analysis (Gravstein, 1995). Upon cross-linking, this antibody has been shown to induce a 4-fold increase in T cell proliferation in response to suboptimal stimulation with concanavalin A (Gravestein, 1995), indicating that this antibody is able to mimic ligand binding.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: CD27 antigen
• Database Link:
  Entrez Gene 21940 Mouse
  UniProt ID P41272
• Synonyms: MGC20393; S152; T14; TNFRSF7; Tp55