EGFR Human Monoclonal Antibody [Clone ID: h-R3 (Nimotuzumab)]
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Product Data | |
Clone Name | h-R3 (Nimotuzumab) |
Applications | FC, IHC |
Reactivities | Human |
Host | Human |
Isotype | IgG1, kappa |
Clonality | Monoclonal |
Immunogen | This antibody we generated by humanisation of the murine antibody R3, raised against EGFR purified from placenta membranes and A431 tumors. |
Specificity | Binds to human EGFR domain III at a site distinct from antibody 7A7 (Ab00134) (Talavera et al. 2011) This antibody binds to human EGFR and inhibits EGF-dependent clonogenic growth of NRK cells and completely blocks EGF stimulated autophosphorylation of the receptor (Fernandez 1992) |
Formulation | PBS with 0.02% Proclin 300. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles. |
Stability | 3 years from dispatch. |
Gene Name | epidermal growth factor receptor |
Database Link | |
Synonyms | ERBB; ERBB1; HER1; mENA; PIG61 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.