Cd276 Rabbit Monoclonal Antibody [Clone ID: MJ18]
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Specifications
Product Data | |
Clone Name | MJ18 |
Applications | FC |
Reactivities | Mouse |
Modifications | This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
Host | Rabbit |
Isotype | IgG, kappa |
Clonality | Monoclonal |
Immunogen | This antibody was generated by immunizing Sprague Dawley rats with B7-H3-Ig, consisting of the extracellular domain (aa1–242 of mouse B7-H3) linked to the Fc portion of mouse IgG2a, emulsified in CFA (Difco). The antibody was selected by its reactivity to mouse B7-H3-transfected cells, but not to parental cells by flow cytometry. |
Specificity | This antibody binds to mouse B7-H3 and does not react with other B7-family molecules. This antibody has been used to detect murine B7-H3 by flow cytometry. It blocks B7-H3 signalling and can supress priming of Th2-responses and thereby the development of asthmatic responses in an ovalbumin-induced asthma model in BALB/c mice. |
Formulation | PBS with 0.02% Proclin 300. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles. |
Stability | 3 years from dispatch. |
Gene Name | CD276 antigen |
Database Link | |
Synonyms | 4Ig-B7-H3; B7-H3; B7H3 |
Reference Data |
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