DARC (ACKR1) Rabbit Monoclonal Antibody [Clone ID: 2C3]

CAT#: TA386147

Recombinant Anti-DARC (Clone 2C3)

Product Images

Western Blot using anti-DARC antibody 2C3 (Ab00893) Human liver lysate samples (35µg protein in RIPA buffer) were resolved on a 10% SDS PAGE gel and blots probed with the chimeric rabbit version of 2C3 (TA386147) at 0.03 µg/ml before detection using an anti-rabbit secondary antibody. A primary incubation of 1h was used and protein was detected by chemiluminescence. The expected running size for DARC is 35.6kDa. TA386147 successfully detected DARC in human liver lysate.

Specifications

Product Data

• Clone Name: 2C3
• Applications: Bl, ELISA, FC
• Reactivities: Human
• Modifications: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
• Host: Rabbit
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Immunogen: CHO cells transfected with cDNA encoding the Duffy glycoprotein.
• Specificity: The antibody binds specifcally to the pentapeptide FEDVW of the Duffy receptor.
  
  The antibody binds to DARC, a glycoprotein chemokine receptor and the only known receptor for Plasmodium vivax.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: atypical chemokine receptor 1 (Duffy blood group)
• Database Link:
  Entrez Gene 2532 Human
  UniProt ID Q4VBN9