CD10 (MME) Rabbit Monoclonal Antibody [Clone ID: NL-1]

CAT#: TA386175

Recombinant Anti-CD10 (Clone NL-1)

Specifications

Product Data

• Clone Name: NL-1
• Applications: IF, IP, WB
• Reactivities: Human
• Modifications: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
• Host: Rabbit
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Immunogen: BALB/c mice were immunised with acute lymphocytic leukaemia cells from a human leukaemia patient. Splenocytes were obtained from immunised mice and fused with MOPC-21 NS/1 myeloma cells to generate a hybridoma.
• Specificity: This antibody reacts with human CD10. CD10 is a widely-expressed cell-surface metalloprotease, responsible for the cleavage of multiple peptide hormones at target tissues. CD10 is also a common marker for acute lymphocytic leukaemia.
  
  NL-1 was shown to react with several leukaemic cell lines using immune adherence assays (Ueda et al, 1982). These authors also confirmed that NL-1 is specific for CD10 using IP.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: membrane metallo-endopeptidase
• Database Link:
  Entrez Gene 4311 Human
  UniProt ID P08473
• Synonyms: atriopeptidase; CALLA; CD10; DKFZp686O16152; Enkephalinase; EPN; MGC126681; MGC126707; NEP; neprilysin