CD15 Rabbit Monoclonal Antibody [Clone ID: BRA-4F1]
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Specifications
Product Data | |
Clone Name | BRA-4F1 |
Applications | FC, IF, IHC, IP |
Reactivities | Human |
Modifications | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgM format, for improved compatibility with existing reagents, assays and techniques. |
Host | Rabbit |
Isotype | IgG, kappa |
Clonality | Monoclonal |
Immunogen | This antibody was raised by immunzing mice with human CD15. |
Specificity | This antibody is specific for CD15 (Appelmelk. et al, 1996, pmid:8675304). It also shows crossreactivity with the CD15 antigen from other species. This antibody has been used in flow cytometry (Appelmelk. et al, 1996). The antibody has been shown to be usefull in immunohistochemistry (Appelmelk. et al, 1996). The antibody is utilized in immunopercipitation (Akin. et al, 2000). Immunofluorescence is a proven application of this antibody (Vilella. et al, 2003). CD15 is expressed in Reed-Sternberg cells, which are a sign of Hodgkin's lymphoma, and thus the antibody can be used in immunohistochemistry to detect this kind of cancer (Trillo-Tinoco. et al, 2019). Finally, BRA-4F1 can be used in fertility research as the CD15 antigen is a molecule that is nessecary for a sperm cell to recognize and fertilize an egg cell. |
Formulation | PBS with 0.02% Proclin 300. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles. |
Stability | 3 years from dispatch. |
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