SF3B4 Mouse Monoclonal Antibody [Clone ID: 3A1]

CAT#: TA389031

Anti-SAP49 Antibody

Specifications

Product Data

• Clone Name: 3A1
• Applications: ICC, IHC, WB
• Recommended Dilution: WB: 1:2000
  ICC: 1:1000
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant full length human SAP49 expressed in and purified from E. Coli.
• Specificity: Specific for endogenous levels of the ~49 kDa SAP49 protein.
• Formulation: PBS + 50% glycerol and 5 mm NaN3
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
• Stability: After date of receipt, stable for at least 1 year at -20°C.
• Predicted Protein Size: 49
• Gene Name: splicing factor 3b subunit 4
• Database Link:
  Entrez Gene 10262 Human
  UniProt ID Q15427
• Background: The spliceosome associated protein of ~49 kDa (SAP49), also known as SF3B4, is a widely expressed nuclear splicing factor that has been shown to have RNA binding activity as well as direct interaction with SAP145 (Champion-Arnaud and Reed 1994). The SAP145-SAP49 complex has recently been implicated in cell cycle progression as Vpr (viral protein 1 of HIV-1) has been shown to bind SAP145 thus interfering with the proper formation and functioning of the SAP145-SAP49 complex (Terada and Yasuda 2006).
• Synonyms: MGC10828; SAP49; SF3b49; SF3b50
• Note: Protein G purified culture supernatant.