VILIP1 (VSNL1) Mouse Monoclonal Antibody [Clone ID: 2D11]

CAT#: TA389038

Anti-Visinin-Like Protein 1 (VSNL1) Antibody

Specifications

Product Data

• Clone Name: 2D11
• Applications: ICC, IHC, WB
• Recommended Dilution: WB: 1:2000
  WB Brain: 1:2000
  ICC: 1:500-1:1000
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human VSNL1 purified from E. coli.
• Specificity: Specific for endogenous levels of the ~22 kDa VSNL1 protein.
• Formulation: PBS + 10 mM NaN3.
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
• Stability: After date of receipt, stable for at least 1 year at -20°C.
• Predicted Protein Size: 22
• Gene Name: visinin like 1
• Database Link:
  Entrez Gene 7447 Human
  UniProt ID P62760
• Background: Visinin-like protein 1 (VSNL1), also known as VILIP1, is a calcium sensor protein expressed exclusively in neurons. Highest levels of VSNL1 expression are found in cerebellar Purkinje cells. VSNL1 has been implicated in the modulation of cell signaling cascades via regulation of adenyl cyclase activity (Braunewell et al., 1997). Additionally, VSNL1 has been associated with amyloid plaques and neurofibrillar tangles in Alzheimer’s disease (Schnurra et al., 2001).
• Synonyms: HLP3; HPCAL3; HUVISL1; OTTHUMP00000200482; OTTHUMP00000200483; VILIP; VILIP-1; VISL1; VLP-1
• Note: Protein G purified culture supernatant.