PKC delta (PRKCD) Rabbit Polyclonal Antibody

CAT#: TA392654

PKC δ (phospho-T505) polyclonal antibody


USD 285.00

4 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications WB
Recommended Dilution WB:1:500~1:1000
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic phosphopeptide derived from human PKC δ around the phosphorylation site of Threonine 505.
Specificity p-PKC δ (T505) polyclonal antibody detects endogenous levels of PKC δ protein only when phosphorylated at Thr505.
Formulation Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration 1mg/ml
Conjugation Unconjugated
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Stability 1 year
Predicted Protein Size ~ 80 kDa
Gene Name protein kinase C delta
Background Protein Kinase C delta (PKC delta) is a 78 kDa member of the novel group (nPKCs: sensitive to diacylglycerol, phosphatidylserine, and phorbol esters) of the PKC family of serine/threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC delta is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of multiple cellular processes including cell cycle progression and apoptosis. Autophosphorylation of serine 664 (serine 662 in mouse and rat) contributes to PKC delta activity. Serum dependent phosphorylation of serine 664 is mediated by mTOR pathway, is protected from dephosphorylation by phosphorylated threonine 505 in the activation loop, and is implicated in prolactin signaling.
Synonyms nPKC-delta; PKCδ; PRKCD; Protein kinase C delta type; SDK1; Sphingosine-dependent protein kinase-1; Tyrosine-protein kinase PRKCD
Note For research use only, not for use in diagnostic procedure.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.