Cytokeratin 8 (KRT8) Rabbit Polyclonal Antibody

CAT#: TA392924

Cytokeratin 8 (phospho-S432) polyclonal antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:1000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic phosphopeptide derived from human Casein Kinase IIβ around the phosphorylation site of Serine 209
• Specificity: Cytokeratin 8 (phospho-S432) polyclonal antibody detects endogenous levels of Cytokeratin 8 protein only when phosphorylated at Ser432.
• Formulation: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Predicted Protein Size: ~ 55 kDa
• Gene Name: keratin 8
• Database Link:
  Entrez Gene 3856 Human
  UniProt ID P05787
• Background: Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments. Keratin isoforms demonstrate tissue and differentiation-specific profiles that make them useful as research biomarkers. Research studies have shown that mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases.
• Synonyms: Casein kinase II subunit beta; CK2N, G5A; CK II beta; CSNK2B; Phosvitin; Protein G5a
• Note: For research use only, not for use in diagnostic procedure.