DDX5 Rabbit Polyclonal Antibody

CAT#: TA392939

p68 RNA Helicase (phospho-Y593) polyclonal antibody


USD 285.00

4 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications WB
Recommended Dilution WB: 1:500~1:1000
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide derived from human p68 RNA Helicase around the phosphorylation site of Y593.
Specificity p68 RNA Helicase (phospho-Y593) polyclonal antibody detects endogenous levels of p68 RNA Helicase protein only when phosphorylated at Tyr593.
Formulation Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration 1mg/ml
Conjugation Unconjugated
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Stability 1 year
Predicted Protein Size ~ 68 kDa
Gene Name DEAD-box helicase 5
Background p68 RNA Helicase is a nuclear protein that exhibits RNA-dependent ATPase activity. Phosphorylation by protein kinase C inhibits p68 RNA Helicase activity. p68 RNA Helicase appears to play a role in organ differentiation during development. Furthermore, p68 RNA Helicase is expressed in early neural development and in various mesodermal tissues in a number of different chordate embryos. At the cellular level, the expression levels of p68 RNA Helicase increase in serum-induced quiescent cell lines. p68 RNA Helicase may function as a coactivator for estrogen receptor α. Additionally, p68 RNA Helicase associates with transcriptional coactivators CBP and p300. p68 RNA Helicase localizes to the nucleus under normal conditions. During late telophase, p68 RNA Helicase and fibrillarin co-localize to nascent nucleoli. p68 RNA Helicase may function as a heterodimer with p72 RNA Helicase.
Synonyms 68kD); ATP dependent RNA helicase DDX5; DDX 5; DDX5; Ddx5; DEAD (Asp Glu Ala Asp) box helicase 5; DEAD (Asp Glu Ala Asp) box polypeptide 5; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase 68kDa); DEAD/H (Asp Glu Ala Asp/His) box polypeptide 5; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 5 (RNA helicase; DEAD/H box-5 (RNA helicase 68kD); DEAD box 5; DEAD box protein 5; DKFZp686J01190; G17P1; HELR; HLR 1; HLR1; HUMP68; P68; p68 RNA he
Note For research use only, not for use in diagnostic procedure.
Reference Data

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