hnRNP K (HNRNPK) Rabbit Polyclonal Antibody

CAT#: TA392959

hnRNP K (phospho-S284) polyclonal antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:1000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic phosphopeptide derived from human hnRNP K around the phosphorylation site of Serine 284
• Specificity: p-hnRNP K (S284) pAb detects endogenous levels of hnRNP K protein only when phosphorylated at Ser284.
• Formulation: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Predicted Protein Size: ~ 58 to 62 kDa
• Gene Name: heterogeneous nuclear ribonucleoprotein K
• Database Link:
  Entrez Gene 3190 Human
  UniProt ID P61978
• Background: The majority of hnRNP proteins components are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm, such as hnRNP K. hnRNP K, a 65 kDa protein, recruits a variety of molecular partners through two K homologous (KH) domains, which are required for protein-protein interactions. hnRNP K also contains several potential phosphorylation sites, including Ser 302, the major site of PKCd phosphorylation, which are thought to regulate various cellular functions, including sequence-specific DNA binding, transcription, RNA binding and nucleocytoplasmic shuttling.
• Synonyms: Heterogeneous nuclear ribonucleoprotein K; HNRNPK; hnRNP K; HNRPK; Transformation up-regulated nuclear protein; TUNP
• Note: For research use only, not for use in diagnostic procedure.