Neurotrophin 3 (NTF3) Mouse Monoclonal Antibody [Clone ID: OTI2D1]

CAT#: TA500031

Anti-NT3 (Neurotrophin 3) mouse monoclonal antibody, clone OTI2D1 (formerly 2D1)

Product Images

NT3 antibody (2D1) at 1:2000 + Recombinant Human NT3 (Cat# RC214281)

Specifications

Product Data

• Clone Name: OTI2D1
• Applications: WB
• Recommended Dilution: WB: 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: Recombinant protein expressed in E.coli corresponding to amino acids 139-257 of human NT3
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 27.4 kDa
• Gene Name: neurotrophin 3
• Database Link:
  NP_001096124
  Entrez Gene 18205 MouseEntrez Gene 81737 RatEntrez Gene 4908 Human
  UniProt ID P20783
• Background: NT3 is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. It is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NT3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse
• Synonyms: HDNF; NGF-2; NGF2; NT-3; NT3

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: MAPK signaling pathway, Neurotrophin signaling pathway