Rad9 (RAD9A) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5D9]

CAT#: TA500435AM

Anti-RAD9A (RAD9) mouse monoclonal antibody, clone OTI5D9 (formerly 5D9), Biotinylated


USD 420.00

4 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name OTI5D9
Applications IHC, WB
Recommended Dilution WB 1:2000 IHC 1:50
Reactivities Human, Monkey, Dog
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human RAD9A expression vector
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 42.5 kDa
Gene Name RAD9 checkpoint clamp component A
Background This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene.
Synonyms RAD9
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.