PKMYT1 Mouse Monoclonal Antibody [Clone ID: OTI2B4]

CAT#: TA500839

PKMYT1 mouse monoclonal antibody, clone OTI2B4 (formerly 2B4)

Size: 30 ul 100 ul

Formulation: Standard Carrier Free


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USD 379.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Clone Name OTI2B4
Applications FC, IF, WB
Recommended Dilution IHC 1:100~200, WB: 1:200
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PKMYT1 (NP_004194) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 54.3 kDa
Gene Name protein kinase, membrane associated tyrosine/threonine 1
Background The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
Synonyms MYT1; PPP1R126
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation

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