TPMT Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2A2]

CAT#: TA500966AM

Anti-TPMT mouse monoclonal antibody, clone OTI2A2 (formerly 2A2), Biotinylated


USD 420.00

4 Weeks*

Size
    • 100 ug

Other products for "TPMT"

Specifications

Product Data
Clone Name OTI2A2
Applications IF, IHC, WB
Recommended Dilution WB 1:1000, IHC 1:50, IF 1:100
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human TPMT (NP_000358) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 28.2 kDa
Gene Name thiopurine S-methyltransferase
Background This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Synonyms OTTHUMP00000016076; S-adenosyl-L-methionine:thiopurine S-methyltransferase; thiopurine methyltransferase; thiopurine S-methyltransferase
Reference Data
Protein Families Druggable Genome
Protein Pathways Drug metabolism - other enzymes

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.