RIC8 (RIC8A) Mouse Monoclonal Antibody [Clone ID: OTI3G3]

CAT#: TA501055

Anti-RIC8A (RIC8) mouse monoclonal antibody, clone OTI3G3 (formerly 3G3)

Size: 30 ul 100 ul

Formulation: Standard Carrier Free


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USD 379.00

In Stock*

Size
    • 100 ul

Other products for "RIC8A"

Specifications

Product Data
Clone Name OTI3G3
Applications IF, IHC, WB
Recommended Dilution WB 1:1000, IHC 1:50, IF 1:100
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human RIC8A (NP_068751) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.83 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 59.6 kDa
Gene Name RIC8 guanine nucleotide exchange factor A
Background Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation
Synonyms RIC8
Reference Data

Other Versions

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