elF2 alpha (EIF2S1) Mouse Monoclonal Antibody [Clone ID: OTI5A5]
CAT#: TA501374
Anti-EIF2S1 mouse monoclonal antibody, clone OTI5A5 (formerly 5A5)
Size: 30 ul
Formulation: Carrier Free
Specifications
Product Data | |
Clone Name | OTI5A5 |
Applications | IHC, WB |
Recommended Dilution | WB 1:1000~2000, IHC 1:50 |
Reactivities | Human, Monkey, Mouse, Rat, Dog |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human EIF2S1 (NP_004085) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.59 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 35.9 kDa |
Gene Name | eukaryotic translation initiation factor 2 subunit alpha |
Database Link | |
Background | The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]). [supplied by OMIM] |
Synonyms | EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A |
Reference Data |
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