IKB zeta (NFKBIZ) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1E8]
Other products for "NFKBIZ"
Specifications
Product Data | |
Clone Name | OTI1E8 |
Applications | FC, WB |
Recommended Dilution | WB 1:500, FLOW 1:100 |
Reactivities | Human, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human NFKBIZ (NP_113607) produced in E.coli. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | HRP |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 77.9 kDa |
Gene Name | NFKB inhibitor zeta |
Database Link | |
Background | This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Synonyms | IKBZ; INAP; MAIL |
Reference Data | |
Protein Families | Druggable Genome |
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