ALDH1A3 Mouse Monoclonal Antibody [Clone ID: OTI4B6]

CAT#: TA502805

ALDH1A3 mouse monoclonal antibody, clone OTI4B6 (formerly 4B6)

Product Images

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-ALDH1A3 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

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  Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-ALDH1A3 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

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  Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-ALDH1A3 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

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  Flow cytometric Analysis of Jurkat cells, using anti-ALDH1A3 antibody (TA502805), (Red), compared to a nonspecific negative control antibody, (Blue).

Specifications

Product Data

• Clone Name: OTI4B6
• Applications: FC, IHC, WB
• Recommended Dilution: WB 1:200, IHC 1:150, FLOW 1:100
• Reactivities: Human, Dog, Monkey, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-100 and 413-512 of human ALDH1A3 (NP_000648) produced in E.coli.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 55.9 kDa
• Gene Name: aldehyde dehydrogenase 1 family member A3
• Database Link:
  NP_000684
  Entrez Gene 100856346 DogEntrez Gene 694231 MonkeyEntrez Gene 220 Human
  UniProt ID P47895
• Background: Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate, either in a free or cellular retinol-binding protein form. [provided by RefSeq, Jul 2008]
• Synonyms: ALDH1A6; ALDH6; MCOP8; RALDH3

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - cytochrome P450, Glycolysis / Gluconeogenesis, Histidine metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Phenylalanine metabolism, Tyrosine metabolism