SIRT6 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1G3]
CAT#: TA503670BM
SIRT6 mouse monoclonal antibody, clone OTI1G3 (formerly 1G3), HRP conjugated
Other products for "SIRT6"
Specifications
Product Data | |
Clone Name | OTI1G3 |
Applications | IF, WB |
Recommended Dilution | WB 1:500~2000, IF 1:100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 88-352 of human SIRT6(NP_057623) produced in E.coli. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | HRP |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 38.9 kDa |
Gene Name | sirtuin 6 |
Database Link | |
Background | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants. |
Synonyms | SIR2L6 |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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