DAND5 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3A3]

CAT#: TA503713BM

DAND5 mouse monoclonal antibody, clone OTI3A3 (formerly 3A3), HRP conjugated

Product Images

Anti-DAND5 mouse monoclonal antibody (TA503713) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DAND5 (RC221703).

• 

  HEK293T cells transfected with either RC221703 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-DAND5 antibody (TA503713), and then analyzed by flow cytometry.

Specifications

Product Data

• Clone Name: OTI3A3
• Applications: FC, IF
• Recommended Dilution: IF 1:100, FLOW 1:100
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 23-189 of human DAND5(NP_689867) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: HRP
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 18 kDa
• Gene Name: DAN domain BMP antagonist family member 5
• Database Link:
  NP_689867
  Entrez Gene 199699 Human
  UniProt ID Q8N907
• Background: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq]
• Synonyms: CER2; CERL2; CKTSF1B3; COCO; CRL2; DANTE; GREM3; SP1