Transferrin Receptor 2 (TFR2) Mouse Monoclonal Antibody [Clone ID: OTI1D8]

CAT#: TA504590

TFR2 (Transferrin Receptor 2) mouse monoclonal antibody, clone OTI1D8 (formerly 1D8)

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TFR2 (RC220060, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TFR2. Positive lysates LY401114 (100ug) and LC401114 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI1D8
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human TFR2(NP_003218) produced in HEK293T cell.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 88.6 kDa
• Gene Name: transferrin receptor 2
• Database Link:
  NP_003218
  Entrez Gene 7036 Human
  UniProt ID Q9UP52
• Background: This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
• Synonyms: HFE3; TFRC2

Reference Data

• Protein Families: Druggable Genome, Protease, Transmembrane