ALX4 Mouse Monoclonal Antibody [Clone ID: OTI2E1]
CAT#: TA505240
ALX4 mouse monoclonal antibody, clone OTI2E1 (formerly 2E1)
Size: 30 ul
Formulation: Carrier Free
Specifications
Product Data | |
Clone Name | OTI2E1 |
Applications | IF, WB |
Recommended Dilution | WB 1:2000, IF 1:100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human ALX4(NP_068745) produced in HEK293T cell. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 44.1 kDa |
Gene Name | ALX homeobox 4 |
Database Link | |
Background | This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq] |
Synonyms | CRS5; FND2 |
Reference Data | |
Protein Families | Druggable Genome |
Documents
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Resources
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