CD3E Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3E10]

CAT#: TA506064AM

CD3E mouse monoclonal antibody,clone 3E10, Biotinylated


USD 420.00

5 Days*

Size
    • 100 ul

Other products for "CD3E"

Specifications

Product Data
Clone Name OTI3E10
Applications IF, IHC, WB
Recommended Dilution WB 1:200~4000, IHC 1:150, IF 1:100
Reactivities Human, Monkey, Dog
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CD3E(NP_000724) produced in HEK293T cell.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 20.7 kDa
Gene Name CD3e molecule
Background The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
Synonyms IMD18; T3E; TCRE
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.