FAK (PTK2) Mouse Monoclonal Antibody [Clone ID: OTI4A8]
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Other products for "PTK2"
Specifications
Product Data | |
Clone Name | OTI4A8 |
Applications | IF, IHC, WB |
Recommended Dilution | WB 1:4000, IHC 1:150, IF 1:100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human PTK2(NP_722560) produced in HEK293T cell. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 119.1 kDa |
Gene Name | protein tyrosine kinase 2 |
Database Link | |
Background | This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010] |
Synonyms | FADK; FAK; FAK1; FRNK; p125FAK; pp125FAK; PPP1R71 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Axon guidance, Chemokine signaling pathway, ErbB signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer, VEGF signaling pathway |
Documents
Product Manuals |
FAQs |
Resources
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