CD163 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2G12]

CAT#: TA506380BM

CD163 mouse monoclonal antibody,clone 2G12, HRP conjugated


USD 462.00

2 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Clone Name OTI2G12
Applications IF, IHC, WB
Recommended Dilution WB 1:1000, IHC 1:150, IF 1:100
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CD163(NP_004235) produced in HEK293T cell.
Formulation PBS (pH 7.4) containing 1% BSA, 50% glycerol.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Store at -20°C as received
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 125.3 kDa
Gene Name CD163 molecule
Background The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Synonyms M130; MM130; SCARI1
Reference Data
Protein Families Druggable Genome, Secreted Protein, Transmembrane

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.