GRF2 (RAPGEF1) Mouse Monoclonal Antibody [Clone ID: OTI2B5]

CAT#: TA506839

RAPGEF1 mouse monoclonal antibody, clone OTI2B5 (formerly 2B5)

Size: 30 ul 100 ul

Formulation: Standard Carrier Free


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USD 379.00

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Size
    • 100 ul

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Specifications

Product Data
Clone Name OTI2B5
Applications IHC, WB
Recommended Dilution WB 1:4000, IHC: 1:150
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human RAPGEF1(NP_941372) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 122.6 kDa
Gene Name Rap guanine nucleotide exchange factor 1
Background This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Synonyms C3G; GRF2
Reference Data
Protein Families Druggable Genome
Protein Pathways Focal adhesion, Insulin signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

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