MINPP1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1B2]

CAT#: TA507234AM

Purified MINPP1 mouse monoclonal antibody, clone OTI1B2 (formerly 1B2), Biotinylated

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MINPP1 (RC207581, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MINPP1. Positive lysates LY417667 (100ug) and LC417667 (20ug) can be purchased separately from OriGene.

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  Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-MINPP1 mouse monoclonal antibody (TA507234) at 1:150 dilution.

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  Anti-MINPP1 mouse monoclonal antibody (TA507234) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MINPP1 (RC207581).

Specifications

Product Data

• Clone Name: OTI1B2
• Applications: IF, IHC, WB
• Recommended Dilution: WB 1:4000, IF 1:100, IHC 1:150
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human MINPP1(NP_004888) produced in HEK293T cell.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 54.9 kDa
• Gene Name: multiple inositol-polyphosphate phosphatase 1
• Database Link:
  NP_004888
  Entrez Gene 9562 Human
  UniProt ID Q9UNW1
• Background: This gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway. [provided by RefSeq, Sep 2009]
• Synonyms: HIPER1; MINPP2; MIPP

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Inositol phosphate metabolism