CYP1B1 Rabbit Polyclonal Antibody

CAT#: TA590005

Rabbit Polyclonal CYP1B1 Antibody

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP1B1 (RC204074, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP1B. Positive lysates LY400032 (100ug) and LC400032 (20ug) can be purchased separately from OriGene.

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  Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CYP1B1 polyclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

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  ELISA: CYP1B1 Antibody

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB 1:5000~20000,ELISA 1:100-1:2000
• Reactivities: Human, Monkey, Mouse, Dog
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: DNA immunization. This antibody is specific for the C Terminus Region of the target protein.
• Formulation: 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
• Concentration: 0.79635 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cytochrome P450 family 1 subfamily B member 1
• Database Link:
  NP_000095
  Entrez Gene 13078 MouseEntrez Gene 483038 DogEntrez Gene 710385 MonkeyEntrez Gene 1545 Human
  UniProt ID Q16678
• Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.
• Synonyms: CP1B; CYPIB1; GLC3A; P4501B1
• Note: This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

• Protein Families: Druggable Genome, P450
• Protein Pathways: Metabolism of xenobiotics by cytochrome P450, Tryptophan metabolism