alpha 1 Fetoprotein (AFP) Rabbit Polyclonal Antibody

CAT#: TA590067

Rabbit Polyclonal Alpha 1 Fetoprotein Antibody


USD 409.00

In Stock*

Size
    • 100 ug

Product Images

Specifications

Product Data
Applications ELISA, WB
Recommended Dilution WB 1:5000,ELISA 1:100-1:2000
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen DNA immunization. This antibody is specific for the N Terminus Region of the target protein.
Formulation 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Concentration 1.02847 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name alpha fetoprotein
Background Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, and pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo and uterus tissue libraries.
Synonyms AFPD; FETA; HPAFP
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
Reference Data
Protein Families Druggable Genome, Secreted Protein

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