CD130 (IL6ST) Rabbit Polyclonal Antibody

CAT#: TA590116

Rabbit Polyclonal CD130 Antibody


USD 409.00

In Stock*

Size
    • 100 ug

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Specifications

Product Data
Applications ELISA, WB
Recommended Dilution WB: 1:5000-1:20000; ELISA: 1:100-1:2000
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen DNA immunization. This antibody is specific for the Middle Region of the target protein.
Formulation 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Concentration 1.1mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name interleukin 6 signal transducer
Background The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
Synonyms CD130; CDW130; GP130; IL-6RB
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
Reference Data
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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