MMP9 Rabbit Polyclonal Antibody

CAT#: TA590194

Rabbit Polyclonal MMP9 Antibody


USD 409.00

In Stock*

Size
    • 100 ug

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Specifications

Product Data
Recommended Dilution WB: 1:5000-1:20000; ELISA: 1:100-1:2000
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen DNA immunization. This antibody was made against a protein fragment from the C Terminus Region
Formulation 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Concentration 0.9854 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name matrix metallopeptidase 9
Background Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP9 degrades of proteins in the extracellular matrix and activates growth factors like proTGF beta and proTNF alpha. MMP9 contributes to the invasion and metastasis of various human malignancies. Clone F37P4A3 has been shown to be useful for western blotting, immunoflorence staining and immunohistochemistry of human, rabbit, dog, and pig acetylated MMP9.
Synonyms CLG4B; GELB; MANDP2; MMP-9
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
Reference Data
Protein Families Druggable Genome, Protease
Protein Pathways Bladder cancer, Leukocyte transendothelial migration, Pathways in cancer

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