p18 INK4c (CDKN2C) Rabbit Polyclonal Antibody

CAT#: TA590417

Rabbit Polyclonal p18 INK4c Antibody

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDKN2C (RC214412, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKN2. Positive lysates LY429933 (100ug) and LC429933 (20ug) can be purchased separately from OriGene.

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  Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CDKN2C polyclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

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  ELISA: p18 INK4c Antibody

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  Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-CDKN2C rabbit polyclonal antibody. (TA590417)

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  Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-CDKN2C rabbit polyclonal antibody. (TA590417)

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  Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-CDKN2C rabbit polyclonal antibody. (TA590417)

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Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB 1:5000~20000, IHC 1:150,ELISA 1:100-1:2000
• Reactivities: Human, Mouse, Dog
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: DNA immunization. This antibody is specific for the C Terminus Region of the target protein.
• Formulation: 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
• Concentration: 1.0219 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cyclin dependent kinase inhibitor 2C
• Database Link:
  NP_523240
  Entrez Gene 12580 MouseEntrez Gene 475359 DogEntrez Gene 1031 Human
  UniProt ID P42773
• Background: p18 INK4c is a specific inhibitor of cdk4 / cdk6 (it interacts strongly with CDK6 and weakly with CDK4), and is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S phase. Highest expression levels are found in skeletal muscle, but it is also found in the pancreas and heart.
• Synonyms: INK4C; p18; p18-INK4C
• Note: This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle