MLN64 (STARD3) Rabbit Polyclonal Antibody

CAT#: TA590564

Rabbit Polyclonal STARD3 Antibody

Product Images

ELISA: STARD3 Antibody

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  Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes. Antibody dilution: 1:100. Image and statement courtesy of the Human Protein Atlas (HPA).

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA: 1:100-1:2000; IHC: 1:10-1:2000; IHC-P 1:10-1:2000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: DNA immunization. This antibody is specific for the C Terminus Region of the target protein.
• Formulation: 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
• Concentration: 1.15mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: StAR related lipid transfer domain containing 3
• Database Link:
  NP_006795
  Entrez Gene 10948 Human
  UniProt ID Q14849
• Background: The steroidogenic acute regulatory (StAR) protein facilitates the movement of cholesterol from the outer to inner mitochondrial membrane in adrenal and gonadal cells, fostering steroid biosynthesis. MLN 64 is a 445-amino acid protein of unknown function. When 218 amino-terminal residues of MLN 64 are deleted, the resulting N-218 MLN 64 has 37% amino acid identity with StAR and 50% of StAR's steroidogenic activity in transfected cells. Bacterially expressed N-218 MLN 64 exerts StAR-like activity to promote the transfer of cholesterol from the outer to inner mitochondrial membrane in vitro. The presence of a protease-resistant domain and a protease-sensitive carboxy-terminal domain in N-218 MLN 64 is similar to the organization of StAR. However, as MLN 64 never enters the mitochondria, the protease-resistant domain of MLN 64 cannot be a mitochondrial pause-transfer sequence, as has been proposed for StAR.
• Synonyms: CAB1; es64; MLN64
• Note: This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

• Protein Families: Transmembrane