SOX2 Rabbit Monoclonal Antibody [Clone ID: OR-4F2]

CAT#: TA591001S

Rabbit monoclonal anti-Sox2 Antibody, clone OTIR094F2

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SOX2 (RC200757, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SOX2 (T. Positive lysates LY401083 (100ug) and LC401083 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OR-4F2
• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Synthetic peptide within Human Sox2 aa 150-200. The exact sequence is proprietary.
• Formulation: Tissue culture buffer containing 1% BSA and 0.02% Sodium azide
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 34.1 kDa
• Gene Name: SRY-box transcription factor 2
• Database Link:
  NP_003097
  Entrez Gene 20674 MouseEntrez Gene 499593 RatEntrez Gene 6657 Human
  UniProt ID P48431
• Background: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]
• Synonyms: ANOP3; MCOPS3

Reference Data

• Protein Families: Adult stem cells, Cancer stem cells, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors