A2ML1 Rabbit Monoclonal Antibody [Clone ID: OTIR2E11]

CAT#: TA591015

Rabbit monoclonal anti-A2ML1 antibody for SISCAPA, clone OTIR2E11

Specifications

Product Data

• Clone Name: OTIR2E11
• Applications: SISCAPA
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Synthetic peptide AGLLTEEIR
• Formulation: Tissue culture buffer containing 1% BSA and 0.02% Sodium azide
• Concentration: Lot dependent; please refer to CoA along with shipment
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 161 kDa
• Gene Name: alpha-2-macroglobulin like 1
• Database Link:
  NP_653271
  Entrez Gene 144568 Human
  UniProt ID A8K2U0
• Background: This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
• Synonyms: CPAMD9; OMS; p170