AMH Capture Rabbit Monoclonal Antibody

CAT#: TA600549

AMH Capture Rabbit Monoclonal antibody, clone OTIR5D9

Product Images

AMH ELISA with 5D9 Capture (TA600549) and 5C11 Detection (TA700549) Antibodies. Substrate used: Recombinant Human AMH (CHO cells expressed protein Cat#TP701045)

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  AMH Luminex ELISA with 5D9 Capture (TA600549) and 5C11 Detection (TA700549) Antibodies. Substrate used: Recombinant Human AMH (CHO cells expressed protein Cat#TP701045)

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  AMH Luminex ELISA with 5D9 Capture (TA600549) and 5C11 Detection (TA700549) Antibodies. Substrate used: AMH Serum

Specifications

Product Data

• Applications: ELISA, LMNX
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant protein (26-560aa) of human AMH produced in HEK293
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
• Predicted Protein Size: 59.17 kDa
• Gene Name: anti-Mullerian hormone
• Database Link:
  NP_000470
  Entrez Gene 268 Human
  UniProt ID P03971
• Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016]
• Synonyms: MIF; MIS

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, TGF-beta signaling pathway