S100 beta (S100B) Capture Mouse Monoclonal Antibody

CAT#: TA600560

S100B Capture Mouse Monoclonal antibody, clone OTI6A6

Product Images

S100B ELISA with 6A6 Capture (TA600560) and 3G6 Detection (TA700560) Antibodies. Substrate used: Recombinant Human S100B (KEK293 cells expressed protein)

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  S100B Luminex ELISA with 6A6 Capture (TA600560) and 3G6 Detection (TA700560) Antibodies. Substrate used: Recombinant Human S100B (KEK293 cells expressed protein)

Specifications

Product Data

• Applications: ELISA, LMNX
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human S100B (NP_006263) produced in HEK293T cell.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
• Predicted Protein Size: 10.7 kDa
• Gene Name: S100 calcium binding protein B
• Database Link:
  NP_006263
  Entrez Gene 6285 Human
  UniProt ID P04271
• Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
• Synonyms: NEF; S100; S100-B; S100beta