ACE2 Mouse Monoclonal Capture Antibody [Clone ID: OTI4C5] (Angiotensin Converting Enzyme 2)

CAT#: TA600564

ACE2 mouse monoclonal antibody, clone OTI4C5

Specifications

Product Data

• Clone Name: OTI4C5
• Applications: ELISA
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment of human ACE2 (NP_068576) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Predicted Protein Size: 92.5 kDa
• Gene Name: angiotensin converting enzyme 2
• Database Link:
  NP_068576
  Entrez Gene 59272 Human
  UniProt ID Q9BYF1
• Background: Angiotensin I-converting enzyme 2 (ACE2) is a protein that belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, ACE2 is a functional receptor for the spike glycoprotein of the human coronaviruses HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2.
• Synonyms: ACEH

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Renin-angiotensin system