BCL10 Mouse Monoclonal Antibody [Clone ID: OTI2B12]

CAT#: TA800447

BCL10 mouse monoclonal antibody, clone OTI2B12 (formerly 2B12)

Size: 30 ul 100 ul

Formulation: Standard Carrier Free


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USD 379.00

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Size
    • 100 ul

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Specifications

Product Data
Clone Name OTI2B12
Applications WB
Recommended Dilution WB: 1:2000
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human BCL10 (NP_003912) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 26.1 kDa
Gene Name B-cell CLL/lymphoma 10
Background This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq]
Synonyms c-E10; CARMEN; CIPER; CLAP; IMD37; mE10
Reference Data
Protein Families Druggable Genome
Protein Pathways B cell receptor signaling pathway, T cell receptor signaling pathway

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