CD23 (FCER2) Mouse Monoclonal Antibody [Clone ID: OTI2H2]

CAT#: TA801572

FCER2 mouse monoclonal antibody, clone OTI2H2 (formerly 2H2)

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FCER2 (RC204335, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FCER2 (1:2000).

• 

  Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-FCER2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, TA801572) (1:500)

• 

  Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-FCER2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, TA801572) (1:500)

Specifications

Product Data

• Clone Name: OTI2H2
• Applications: IHC, WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 48-321 of human FCER2 (NP_001993) produced in Insect.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 36.3 kDa
• Gene Name: Fc fragment of IgE receptor II
• Database Link:
  NP_001993
  Entrez Gene 2208 Human
  UniProt ID P06734
• Background: The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul
• Synonyms: BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF

Reference Data

• Protein Families: Secreted Protein, Transmembrane
• Protein Pathways: Hematopoietic cell lineage