APC Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1B12]

CAT#: TA803682AM

APC mouse monoclonal antibody, clone OTI1B12 (formerly 1B12), Biotinylated

Product Images

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-APC mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA803682)

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  Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-APC mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA803682)

Specifications

Product Data

• Clone Name: OTI1B12
• Applications: IHC
• Recommended Dilution: IHC 1:150
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 955-1382 of human APC (NP_001120983) produced in E.coli.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 311.5 kDa
• Gene Name: adenomatous polyposis coli
• Database Link:
  NP_001120983
  Entrez Gene 11789 MouseEntrez Gene 24205 RatEntrez Gene 324 Human
  UniProt ID P25054
• Synonyms: BTPS2; DP2; DP2.5; DP3; GS; PPP1R46

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Pathways in cancer, Regulation of actin cytoskeleton, Wnt signaling pathway