Macrophage Inflammatory Protein 3 beta (CCL19) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI6A3]

CAT#: TA804342AM

Purified CCL19 mouse monoclonal antibody, clone OTI6A3 (formerly 6A3), Biotinylated

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CCL19 (RC206523, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CCL19. Positive lysates LY401889 (100ug) and LC401889 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI6A3
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 22-98 of human CCL19 (NP_006265) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 8.8 kDa
• Gene Name: C-C motif chemokine ligand 19
• Database Link:
  NP_006265
  Entrez Gene 6363 Human
  UniProt ID Q99731
• Background: This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Jul 2008]
• Synonyms: CKb11; ELC; MIP-3b; MIP3B; SCYA19

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction