Macrophage Inflammatory Protein 3 beta (CCL19) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4F3]

CAT#: TA804426AM

CCL19 mouse monoclonal antibody, clone OTI4F3 (formerly 4F3), Biotinylated

Product Images

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-CCL19 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA804426)

Specifications

Product Data

• Clone Name: OTI4F3
• Applications: IHC
• Recommended Dilution: IHC 1:150
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 22-98 of human CCL19 (NP_006265) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 8.8 kDa
• Gene Name: C-C motif chemokine ligand 19
• Database Link:
  NP_006265
  Entrez Gene 6363 Human
  UniProt ID Q99731
• Background: This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Jul 2008]
• Synonyms: CKb11; ELC; MIP-3b; MIP3B; SCYA19

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction