Protein Z (PROZ) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1C10]

CAT#: TA806764BM

PROZ mouse monoclonal antibody, clone OTI1C10 (formerly 1C10), HRP conjugated

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PROZ (RC210379, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PROZ (1:2000). Positive lysates LY401283 (100ug) and LC401283 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI1C10
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 115-400 of human PROZ(NP_003882) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: HRP
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 40.3 kDa
• Gene Name: protein Z, vitamin K dependent plasma glycoprotein
• Database Link:
  NP_003882
  Entrez Gene 8858 Human
  UniProt ID P22891
• Background: This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
• Synonyms: PZ

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein