VEGF Receptor 1 (FLT1) Mouse Monoclonal Antibody [Clone ID: OTI11G5]
CAT#: TA806786
FLT1 mouse monoclonal antibody, clone OTI11G5 (formerly 11G5)
Size: 30 ul
Formulation: Carrier Free
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Specifications
Product Data | |
Clone Name | OTI11G5 |
Applications | WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 781-1338 of human FLT1 (NP_002010) produced in HEK293T cell. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | fms related tyrosine kinase 1 |
Database Link | |
Background | This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. [provided by RefSeq, May 2009] |
Synonyms | FLT; FLT-1; VEGFR-1; VEGFR1 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase, Secreted Protein |
Protein Pathways | Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion |
Documents
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Resources
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