Dishevelled 2 (DVL2) Mouse Monoclonal Antibody [Clone ID: OTI2D11]

CAT#: TA806791S

DVL2 mouse monoclonal antibody, clone OTI2D11 (formerly 2D11)

Size: 30 ul 100 ul


  View other "OTI2D11" antibodies (2)

USD 159.00

2 Days*

Size
    • 30 ul

Product Images

Frequently bought together (3)
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Specifications

Product Data
Clone Name OTI2D11
Applications IHC
Recommended Dilution IHC 1:150
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-320 of human DVL2(NP_004413) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 78.8 kDa
Gene Name dishevelled segment polarity protein 2
Background This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008]
Synonyms dishevelled; dishevelled 2; dishevelled 2 (homologous to Drosophila dsh); DSH homolog 2; dsh homolog 2 (Drosophila); segment polarity protein dishevelled homolog DVL-2
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS
Protein Pathways Basal cell carcinoma, Colorectal cancer, Melanogenesis, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.